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The OneFlorida Clinical Research Consortium’s Commitment to Community-based Pragmatic Clinical Trials and Implementation Science

Traditional clinical research has focused heavily on determining the efficacy of interventions, and clinical guidelines have been developed to guide health care providers based on these results. Unfortunately, these studies are often carried out in atypical settings, such as large academic health centers with a restricted patient population and intensive human and financial resource support. This type of scenario is often quite different from what community health care providers experience at their practices—where resources are limited, the patient population is heterogeneous and patients have limited means to proceed with recommended changes or referrals. Thus, the success of many promising interventions is highly variable and most often minimized at the local, community-practice level.

The OneFlorida Clinical Research Consortium, which is led by the University of Florida Clinical and Translational Research Institute and includes the University of Florida, Florida State University and the University of Miami, was developed to address the need for research and support to translate the evidence-base gained in these “atypical” academic environments to the community practices of Florida. Its central aim is to facilitate a multi-way exchange of information between academic health research teams, community practices and patients and thereby accelerate the translation of health care research findings to diverse health care settings across the state. OneFlorida partners encompass 22 hospitals, 416 clinic settings and 3,250 physician providers, which provide care for more than 10 million patients across Florida’s 67 counties. Together, OneFlorida partners cover 39 percent of the patient population in what will soon be the nation’s third largest state, including three majority-minority metropolitan areas (Jacksonville, Orlando and Miami) and rural practices throughout the state.

Interested in becoming involved? Email us at for any questions you may have.