Who We Are

The OneFlorida Clinical Research Consortium is a collaboration among researchers, clinicians and patients in Florida to create an enduring infrastructure for a wide range of health research, including pragmatic clinical trials, comparative effectiveness research, implementation science studies, observational research, and cohort discovery. Consortium partners include the University of Florida, Florida State University, the University of Miami, and the University of South Florida, along with the four universities’ affiliated health systems and practices. Other partners include AdventHealth (Orlando), Tallahassee Memorial HealthCare, Tampa General Hospital, Bond Community Health (Tallahassee), Community Health IT (Kennedy Space Center), Nicklaus Children’s Hospital (Miami), Capital Health Plan (Tallahassee), and the Florida Agency for Health Care Administration, which oversees the Florida Medicaid Program.

OneFlorida partners are committed to conducting stakeholder-engaged research in partnership with health systems, clinicians, patients, payers, policymakers and communities. Our partners strive for efficiency, offering multiple approaches and tools to facilitate health care research for today’s complex health issues. Consortium partners also ensure that lessons from research conducted in the state’s diverse settings are systematically captured and translated back into improved health, health care and health policy for Floridians.

Consortium Partners

University of Florida and UF Health
Florida State University and the Regional Campus Practice Partners
University of Miami and UHealth
Orlando Health System
Tallahassee Memorial HealthCare
Tampa General Hospital
Bond Community Health Center Inc.
Nicklaus Children's Hospital
CommunityHealth IT
Capital Health Plan
University of South Florida and USF Health

What We Do

The OneFlorida Clinical Research Consortium unites researchers, clinicians, patients and stakeholders to address some of the nation’s biggest health challenges and serve as a resource for the state in improving health, health care and health policy. Together, OneFlorida partners provide health care to more than 74% of Floridians in the nation’s third largest state. To support research aimed at addressing the state’s most pressing health care needs, OneFlorida’s research infrastructure allows investigators to:

  • Identify cohorts and conduct observational research using aggregate and limited patient-level health data from diverse partners across the state.
  • Identify and intervene with patients at the point of care.
  • Conduct pragmatic clinical trials and other interventional studies, including implementation science and comparative effectiveness research, in eligible, research-ready clinics.


The OneFlorida Data Trust’s repository of statewide health-care data is regularly updated with the inclusion of new partners and data refreshes from existing partners. All data are cleaned, transformed, curated and contained in a centralized data warehouse, allowing streamlined inquiries and uniform results based on high-quality data. Legal agreements for data use and use of OneFlorida’s centralized IRB have already been negotiated with all partners, reducing paperwork and administrative burden.

Scientists and clinicians across Florida rely on the OneFlorida Data Trust to support a variety of research activities, including hypothesis generation, cohort discovery, prep-to-research activities, participant enrollment, observational studies, research workflow (such as informed consent and eligibility determination), and study data collection.


The Data Trust complements the consortium’s Practice-Based Research Network (PBRN), one of 178 national PBRNs registered with the Agency for Healthcare Research and Quality (AHRQ). The OneFlorida PBRN facilitates the conduct of pragmatic clinical trials and other interventional studies in the consortium’s research-ready clinics. Research is conducted in real-world settings to promote the uptake and sustainability of evidence-based health care practices.

The OneFlorida PBRN is managed by the AHRQ’s Integrated Clinical Research Program, which coordinates a variety of research supports designed to create an efficient and streamlined process for practice and patient recruitment, data collection and assessment of patient outcomes.

Intervention sites include academic health care centers and affiliated clinics, private health systems and clinics, public health care systems and clinics, community health centers, and physician-owned practices.


The consortium is governed by the OneFlorida Executive Committee, which adopted a partnership governance model and includes representatives from all partners. The committee oversees the development and utilization of the consortium’s infrastructure cores as well as research alliances created among consortium partners. The committee is co-chaired by Elizabeth Shenkman, Ph.D., co-director of the University of Florida Clinical and Translational Science Institute (UF CTSI), William Hogan, M.D., director of biomedical informatics for the UF CTSI, and Jeffrey Joyce, senior associate dean for research and graduate programs at Florida State University.

Tolulope A. Adebanjo
Orlando Health
Matthew L. Anderson
University of South Florida
University of Florida
University of Miami
University of Florida
Bill Hogan
University of Florida
Kristin Herman
Tallahassee Memorial Healthcare
University of Miami
Florida State University
Florida Agency for Health Care Administration
Nishit S. Patel
University of South Florida
Temple Robinson
Bond Community Health Center, Inc.
Daria Salyakina
Nicklaus Children's Health System
Kendra Siler
Community Health IT
University of Florida
Steven Smith
Florida Hospital
Tallahassee Memorial Hospital
David Willis
David Willis
University of South Florida
Ross Brownson
Washington University
Peter Embi
Regenstrief Institute Inc.
Gary Freed
University of Michigan
Electra Paskett
The Ohio State University
Graham Warren
Medical University of South Carolina
Albert Wu
John Hopkins University