OneFlorida+ i2b2

Informatics for Integrating Biology and the Bedside (i2b2)  

The OneFlorida+ Data Trust houses electronic health records and other data from across OneFlorida+’s partner sites, providing scientists and clinicians with a rich repository of healthcare data and a powerful tool for research. This secure, clinical data warehouse aggregates data from OneFlorida+’s clinical and administrative information systems. OneFlorida+ i2b2 cohort discovery tool provides access to a curated dataset of 16 million patient records that date back to 2012. OneFlorida+ i2b2 data is refreshed quarterly, after PCORI data characterization.

OneFlorida+ i2b2 houses patient demographics, enrollment data, dispensing data, vitals, conditions, encounters, diagnosis, procedures, lab results, prescribing data, death data, clinical observations and medication administration for UF Health, Capital Health Plan, Florida Medicaid, Florida Hospital/AdventHealth, Nicklaus Children’s, Orlando Health, Tallahassee Memorial Healthcare and University of Miami Health.

The OneFlorida+ i2b2 research tool provides a quick and easy way for researchers to access and query the IDR directly for cohort discovery and prep-to-research. Using the i2b2 tool, researchers can identify patient populations and the occurrence of incidents over time:  How many patients with hypertension are in our catchment area? How many have particular complications? How many have tissue in our biorepository? I2b2 queries provide researchers with limited datasets that give an estimate of the number of patients that match the search criteria without revealing patient identifiers.

Please note, the date ranges in i2b2 are reflected at the top banner of OneFlorida+ i2b2 . 

Examples of queries

Search criteria can include patient demographics, IDC-9 coded diagnoses, CPT and HCPCS-coded procedures.


Need help setting up your search? Click below to access our training videos, user guides, and CDM guides for data tables and information. Coming soon: Additional training videos for conducting more advanced searches.

Accessing i2b2 (aggregate counts)

i2b2 access request form

Accessing the patient-level dataset

If you find that you want to explore the cohort on an individual level and want to obtain a limited dataset, please complete a research application here:

You can upload your specific query search to the research application.  Please allow at least three weeks for approval and a letter of support after you submit your materials.  The application will undergo administrative and scientific review to provide an estimate for services, feasibility assessments, a letter of support, and a letter of approval.

To obtain a limited dataset using the OneFlorida+ i2b2 research tool, researchers must be affiliated with one of our partner sites.

Next Steps

To request a patient level dataset please do the following:

  1. Save your query report to submit with your research application.
  2. Complete a research application
  3. You will receive an email confirmation of your submission.

Contact us

Email the OneFlorida+ i2b2 team for login issues or issues with query performance:

Email the OneFlorida+ Front Door team to register additional study staff:

For questions about the OneFlorida+ Clinical Research Network, the OneFlorida+ Data Trust or to submit a request for patient-level data,  contact or visit our website

i2b2 Server Maintenance

Wednesdays – 8-9 a.m. i2b2 Server Maintenance Window

Description: The OneFlorida+ i2b2 query tool services MAY be down periodically each Wednesday morning between 8 and 9 a.m. for maintenance. Typically, this maintenance will occur just once per month and last 5 minutes or less. During this time, the server may reboot suddenly, causing a loss of work or brief unavailability of i2b2 query tool services. You may continue to use the tool during this maintenance window, but with the caveat that you risk losing your work if a reboot occurs.

Impacts: All users of OneFlorida+ i2b2 services. The online query tool may be unavailable or reboot suddenly during this time, even if you have work in progress.

Acknowledgments for publications

Please use the following language in your acknowledgments:

Research reported in this publication was supported in part by the OneFlorida+ Clinical Data Network, funded by the Patient-Centered Outcomes Research Institute #CDRN-1501-26692, in part by the OneFlorida Cancer Control Alliance, funded by the Florida Department of Health’s James and Esther King Biomedical Research Program #4KB16, and in part by the University of Florida Clinical and Translational Science Institute, which is supported in part by the NIH National Center for Advancing Translational Sciences under award number UL1TR001427. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Patient-Centered Outcomes Research Institute (PCORI), its Board of Governors or Methodology, the OneFlorida+ Clinical Research Network, the University of Florida’s Clinical and Translational Science Institute, the Florida Department of Health, or the National Institutes of Health.

“Copyright Cerner Multum, Inc. All rights reserved.”

Citing the Data Trust

DOI number  10.6084/m9.figshare.7025861