Publications

2021

The OneFlorida Data Trust: a centralized, translational research data infrastructure of statewide scope
William R. Hogan, Elizabeth A. Shenkman, Temple Robinson, Olveen Carasquillo, Patricia S. Robinson, Rebecca Z Essner, Jiang Bian, Gigi Lipori, Christopher Harle, Tanja Magoc, Lizabeth Manini, Tona Mendoza, Sonya White, Alex Loiacono, Jackie Hall, and Dave Nelson
JAMIA, October 19, 2021

Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19: The ACTIV-4B Randomized Clinical Trial
Jean M. Connors, Maria M. Brooks, Frank C. Sciurba, Jerry A. Krishnan, Joseph R. Bledsoe, Andrei Kindzelski, Amanda L. Baucom, Bridget-Anne Kirwan, Heather Eng, Deborah Martin, Elaine Zaharris, Brendan Everett, Lauren Castro, Nancy L. Shapiro, Janet Y. Lin, Peter C. Hou, Carl J. Pepine, Eileen Handberg, Daniel O. Haight, Jason W. Wilson, Sarah Majercik, Zhuxuan Fu, Yongqi Zhong, Vidya Venugopal, Scott Beach, Steve Wisniewski, Paul M. Ridker, the ACTIV-4B Investigators
JAMA, October 11, 2021

Learning the Language of Science: A Pilot Study Exploring Citizen Scientists’ Identity and Communication with Researchers
Rachel Damiani, Janice L. Krieger, Debbie Treise, Kim Walsh-Childers, Carla L. Fisher, Shirley Bloodworth, Janet Brishke, and Elizabeth Shenkman
Cambridge University Press, September 13, 2021

P09.02 An Evaluation Algorithm to Define Clinical Utility of Lung Nodule Diagnosis in a Multi-Collaborator Setting Using Real World Data
Christina M. Godfrey, Stephen Deppen, Kim Rieger-Christ, Yi Guo, Jiang Bian, Edward Frankenberger, Jennifer Woodard, Chad Dorn, Susan Robbins, Susan Gawel, Gerard Davis
International Association for the Study of Lung Cancer, Poster Presentation, September 9, 2021 Vol 16, Issue 10, Supplement, S994-S995

Implementation Context for Addressing Social Needs in a Learning Health System: A Qualitative Study
Ryan P. Theis, Katherine Blackburn, Gloria Lipori, Christopher A. Harle, Michelle M. Alvarado, Peter J. Carek, Nadine Zemon, Angela Howard, Ramzi G. Salloum, Elizabeth A. Shenkman and the UF CTSI Learning Health System Program
Cambridge University Press, August 31, 2021

Ambient Heat and Stillbirth in Northern and Central Florida
David A. Savitz, Hui Hu
Environmental Research, Volume 199, August 2021

Testing the Use of Data Drawn from the Electronic Health Record to Compare Quality
Kathleen E. Walsh, Hanieh Razzaghi, David M. Hartlet, Levon Utidjian, Shannon Alford, Rahul A. Darwar, Elizabeth Shenkman, Susannah Jonas, Mary Goodick, Jonathan Finkelstein, Al Ozonoff, L. Vandy Black, Michael Shapiro, Kathryn Shaw, Jennifer McCafferty-Fernandez, Keith Marsolo, Amy Kelly, Lloyd N. Werk, Jordan Smallwood, and Charles Bailey
Pediatric Quality & Safety 2021 Jul-Aug, July 28, 2021

Validate Real-World Data-based Endpoint Measures of Cancer Treatment Outcomes
Qian Li, Hansi Zhang, Zhaoyi Chen, Yi Guo, Thomas J George Jr., Yong Chen, Fei Wang, Jiang Bian
AMIA Annu Symp Proc 2021, June 16, 2021

Accessing Artificial Intelligence for Clinical Decision-Making
Chris Giordano, Meghan Brennan, Basma Mohamed, Parisa Rashidi, Francois Modave & Patrick Tighe
Frontiers in Digital Health, 3, 65. June 25, 2021

Examination of Early CNS Symptoms and Severe Coronavirus Disease 2019: A Multicenter Observational Case Series
David E. Marra, Katharina M. Busl, Christopher P. Robinson, Maria J. Bruzzone, Amber H. Miller, Zhaoyi Chen, Yi Guo, Tianchen Lyu, Jiang Bian, and Glenn E. Smith
Critical Care Explorations, Vol. 3, No. 6, June 2021

590-P Disparities in the Utilization of Bariatric Surgery among Obese Patients with or without Type 2 Diabetes: Evidence from the OneFlorida Clinical Research Consortium
Guanming Chen, William T. Donahoo, Michelle Cardel, Allison Holgerson, Alexander L. Ayzengart and Matthew J. Gurka
American Diabetes Association, Poster Presentations: Clinical Diabetes/Therapeutics 2021 Jun; 70 (supplement 1)

Abstract 042: Do Disparities In Cardiovascular Comorbidities Account For Excess Covid-19 Morbidity and Mortality in African Americans?
Osama Dasa, Scott A. Cohen, Yi Zheng, Ruba Sajdeya, Mohamed B Taha, Hui Hu, Thomas A. Pearson
Circulation, Oral Abstract Presentations, May 25, 2021 Vol 143, Issue Suppl_1

Exploring the Feasibility of Using Real-World Data from a Large Clinical Data Research Network to Simulate Clinical Trials of Alzheimer’s Disease
Zhaoyi Chen (co-first), Hansi Zhang (co-first), Yi Guo, Thomas J. George, Mattia Prosperi, William R. Hogan, Zhe He, Elizabeth A. Shenkman, Fei Wang and Jiang Bian
Nature npj Digital Medicine, Vol. 4, No. 84, May 14, 2021

Machine learning enabled subgroup analysis with real-world data to inform better clinical trial design
Jie Xu, Hao Zhang, Hansi Zhang, Jiang Bian, & Fei Wang
MedRxiv – Preprint, May 12, 2021

Central Nervous System Manifestations of COVID-19: A Critical Review and Proposed Research Agenda
Kelsey C. Hewitt, David E. Marra, Cady Block, Lucette A. Cysique, Daniel L. Drane, Michelle M. Haddad, Emilia Lojek, Carrie R. McDonald, Anny Reyes, Kara Eversole & Dawn Bowers
Journal of the International Neuropsychological Society, April 16, 2021

21614 Use of an Outcomes Continuum to Describe Disparities in CVOID-19: Data from the OneFlorida Research Consortium
Osama Dasa, Scott Cohen, Ruba Sajdeya, Yi Zheng, Mohamed B. Taha and Thomas A. Pearson
Cambridge University Press – Research Abstract Published online, March 30, 2021

73662 Racial Disparities in Spectic Shock Mortality: Results from the OneFlorida Data Trust Cohort
Lauren Page Black, Charlotte Hopson, Elizabeth DeVos, Michael Puskarich, Rosemarie Fernandez, Faheem Guirgis, and Cynthia Garvan
Cambridge University Press – Research Abstract Published online, March 30, 2021

An Efficient and Accurate Distributed Learning Algorithm for Modeling Multi-Site Zero-Inflated Count Outcomes
Mackenzie J. Edmondson, Chongliang Luo, Rui Duan, Mitchell Maltenfort, Zhaoyi Chen, Kenneth Locke, Justine Shults, Jiang Bian, Patrick Ryan, Christopher B. Forrest, & Yong Chen
MedRxiv – Preprint, March 27, 2021

Newly diagnosed cardiovascular disease in patients treated with immune checkpoint inhibitors: a retrospective analysis of patients at an academic tertiary care center
Nida Waheed, Michael G. Fradley, David L. DeRemer, Ahmad Mahmoud, Chintan P. Shah, Taimour Y. Langaee, Gloria P. Lipori, Keith March, Carl J. Pepine, Rhonda M. Cooper-DeHoff, Yonghui Wu, Yan Gong
Cardio-Oncology, Volume 7, No. 10, 2021

Identifying new risk factors for early-onset CRC in population under 50 years old using EHR-based machine learning
Michael B. Quillen, Taylor M. Parker, Jiang Bian and Thomas George
Research abstract presented at AACR Virtual Special Conference on Artificial Intelligence, Diagnosis, and Imaging; January 13-14, 2021; Clinical Cancer Research, March 2021

Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease
W. Schuyler Jones, Hillary Mulder, Lisa M. Wruck, Michael J. Pencina, Sunil Kripalani, Daniel Muñoz, David L. Crenshaw, Mark B. Effron, Richard N. Re, Kamal Gupta, R. David Anderson, Carl J. Pepine, Eileen M. Handberg, Brittney R. Manning, et al.

Following the Breadcrumbs of Palliative Care Financial Sustainability to Big Data
Sheri Kittelson, Brian Cassel, Phillip Rodgers, Tamara Macieira, Ramzi G. Salloum, Christopher R. Cogle, Yingwei Yao, Elizabeth Anne Shenkman, Diana Wilkie
Journal of Palliative Medicine, Volume 24, Number 5, 2021

Rationale and Design of the Women’s IschemiA TRial to Reduce Events In Non-ObstRuctive CAD (WARRIOR) Trial
Eileen M. Handberg, C. Noel Bairey Merz, Rhonda Cooper-Dehoff, Janet Wei, Michael Conlon, Margaret C. Lo, William Boden, Susan M. Frayne, Todd Villines, John A. Spertus, William Weintraub, Patrick O’Malley, Bernard Chaitman, Leslee J. Shaw, Matthew Budoff, Andre Rogatko, Carl J.Pepine

Abstract PO-10: Identifying new risk factors for early-onset CRC in population under 50 years old using EHR-based machine learning
Michael B. Quillen, Taylor M. Parker, Jiang Bian, and Thomas George
Clinical Cancer Research, Oral Presentations, March 2021 Volume 27, Issue 5 Supplement

Abstract PO-071: Simulation of colorectal cancer clinical trials using real-world data and machine learning
Zhaoyi Chen, Hansi Zhang, Thomas George, Mattia Prosperi, Yi Guo, Dejana Braithwaite, Elizabeth Shenkman, Jonathan Licht, and Jiang Bian
Clinical Cancer Research, Poster Presentations, March 2021 Volume 27, Issue 5 Supplement

Machine Learning Algorithms to Define Colorectal Cancer Risk Factors
Warren Froelich
Oncology Times, Vol. 43, No. 5, March 5, 2021

Direct‐Acting Antiviral Treatment Use Remains Low Among Florida Medicaid Beneficiaries with Chronic Hepatitis C
Haesuk Park, Xinyi Jiang, Hyun Jin Song, Vincent Lo Re, Lindsey M. Childs‐Kean, Wei‐Hsuan Lo‐Ciganic, Robert L. Cook, David R. Nelson

Optimizing Precision of Hypertension Care to Maximize Blood Pressure Control: A Pilot Study Utilizing a Smartphone App to Incorporate Plasma Renin Activity Testing
Mai Mehanna, Yiqing E. Chen, Yan Gong, Eileen Handberg, Brittney Roth, Jessica De Leon, Steven M. Smith, Jonathan G. Harrell and Rhonda M. Cooper-DeHoff

Sex Differences in Co-occurring Conditions Among Autistic Children and Youth in Florida: A Retrospective Cohort Study (2012–2019)
Amber M. Angell, Alexis Deavenport-Saman, Larry Yin, Baiming Zou, Chen Bai, Deepthi Varma & Olga Solomon

PCORnet® 2020: current state, accomplishments, and future directions
Christopher B. Forrest, Kathleen M. McTigue, Adrian F. Hernandez, Lauren W. Cohen, Henry Cruz, Kevin Haynes, Rainu Kaushal, Abel N. Kho, Keith A. Marsolo, Vinit P. Nair, Richard Platt, Jon E. Puro, Russell L. Rothman, Elizabeth A. Shenkman, Lemuel Russell Waitman, Neely A. Williams, Thomas W. Carton

2020

947. Stroke demographics and risk factor profile in HIV infected individuals in Florida
Folusakin Ayoade, MD and Dushyantha Jayaweera, MD
Open Forum Infect Dis. 2020 Oct; 7(Suppl 1):S506 Published online December 31, 2020

Association Between Residential Neighborhood Social Conditions and Health Care Utilization and Costs
Yongkang Zhang, Jessica S. Ancker, Jaclyn Hall, Dhruv Khullar, Yiyuan Wu, Rainu Kaushal

The Impact of Social and Clinical Complexity on Diabetes Control Measures
Erika K. Cottrell, Jean P. O’Malley, Katie Dambrun, Brian Park, Michelle A. Hendricks, Hongzhi Xu, Mary Charlson, Andrew Bazemore, Elizabeth Ann Shenkman, Abby Sears and Jennifer E. DeVoe

Developing an actionable patient taxonomy to understand and characterize high-cost Medicare patients
Yongkang Zhanga, Zachary Grinspan, Dhruv Khullar, Mark Aaron Unruh, Elizabeth Shenkman, Andrea Cohen, Rainu Kaushal

Distributed Learning from Multi-Site Observational Health Data for Zero-Inflated Count Outcomes
Mackenzie J. Edmondson, Chongliang Luo, Rui Duan, Mitchell Maltenfort, Zhaoyi Chen, Justine Shults, Jiang Bian, Patrick B. Ryan, Christopher B. Forrest, Yong Chen

Cardiotoxicity associated with immune checkpoint inhibitors: A retrospective analysis of patients at an academic tertiary care center
Nida Waheed, Michael G. Fradley, David DeRemer, Ahmad Mahmoud,Chintan P. Shah, Taimour Y. Langaee, Gloria P. Lipori, Keith March, Carl J. Pepine, Rhonda M. Cooper-DeHoff, Yonghui Wu, Yan Gong

Abstract 16720: Cardiovascular Toxicities of Cyclin Dependent Kinase (cdk) 4/6 Inhibitors in Metastatic Breast Cancer Patients
Michael G Fradley, Nam Nguyen, Yiqing Chen, Avirup Guha, Jenica N Upshaw, Bonnie Ky, Yan Gong
Circulation, Session Title: At the Heart of Malignancies: Cross Talk Between Cancer and Heart Disease, November 17, 2020 Vol 142, Issue Suppl_3

Abstract 16457: Racial/Ethnic Differences in Cardiac Surveillance Evaluation for Cancer Patients Treated With Anthracycline-based Chemotherapy: The Oneflorida Clinical Research Consortium
Nam K Nguyen, Michael G Fradley, Yiqing Chen, David DeRemer, Nida Waheed, Taimour Y Langaee, Faraz S Ahmad, Rhonda M Cooper-dehoff, Carl J Pepine, Yan Gong
Circulation, Session Title: Harnessing Big Data, Machine Learning and Immunotherapies to Improve Cardio-Oncologic Outcomes, November 17, 2020 Vol 142, Issue Suppl_3

Framework for a Community Health Observing System for the Gulf of Mexico Region: Preparing for Future Disasters
Paul Sandifer, Landon Knapp, Maureen Lichtveld, Ruth Manley, David Abramson, Rex Caffey, David Cochran, Tracy Collier, Kristie Ebi, Lawrence Engel, John Farrington, Melissa Finucane, Christine Hale, David Halpern, Emily Harville, Leslie Hart, Yulin Hswen, Barbara Kirkpatrick, Bruce McEwen, Glenn Morris, Raymond Orbach, Lawrence Palinkas, Melissa Partyka, Dwayne Porter, Aric A. Prather, Teresa Rowles, Geoffrey Scott, Teresa Seeman, Helena Solo-Gabriele, Erik Svendsen, Terry Tincher, Juli Trtanj, Ann Hayward Walker, Rachel Yehuda, Fuyuen Yip, David Yoskowitz, and Burton Singer
Frontiers in Public Health, 8, 588. October 15, 2020

One size does not fit all: Insights for engaging front-line clinicians in pragmatic clinical trials
Ellen Tambor, Rachael Moloney, and Sarah M. Greene
Learning Health Systems, e10248, October 13, 2020

Exploration of PCORnet Data Resources for Assessing Use of Molecular-Guided Cancer Treatment
Ryan M. Carnahan, Lemuel R. Waitman, Mary E. Charlton, Mary C. Schroeder, Aaron D. Bossler, W. Scott Campbell, James R. Campbell, Bradley D. McDowell, Nicholas C. Smith, Brian M. Gryzlak, Elizabeth A. Chrischilles

International Classification of Diseases, Tenth Revision, Clinical Modification social determinants of health codes are poorly used in electronic health records
Yi Guo, Zhaoyi Chen, Ke Xu, Thomas J. George, Yonghui Wu, William Hogan, Elizabeth A. Shenkman, and Jiang Bian

Applications of artificial intelligence in drug development using real-world data
Zhaoyi Chen, Xiong Liu, William Hogan, Elizabeth Shenkman, Jiang Bian

Assessing the practice of data quality evaluation in a national clinical data research network through a systematic scoping review in the era of real-world data
Jiang Bian,  Tianchen Lyu,  Alexander Loiacono,  Tonatiuh Mendoza Viramontes,  Gloria Lipori, Yi Guo,  Yonghui Wu,  Mattia Prosperi,  Thomas J George, Jr,  Christopher A Harle, Elizabeth A Shenkman,  William Hogan

Utilizing electronic medical record data to predict onset of Alzheimer’s disease and related dementias
David E Marra, Amber H. Miller, Qian Li, Xi Yang, Glenn E. Smith, Yonghui Wu, Jiang Bian, Demetrius M Maraganore

A time series analysis of the ecologic relationship between acute and intermediate PM2.5 exposure duration on neonatal intensive care unit admissions in Florida
Eric S. Coker, James Martin, Lauren D. Bradley, Karen Sem, Kayan Clarke, Tara Sabo-Attwood

Understanding resistance, resilience and repair: An analysis of electronic medical records to identify ‘successful aging’ free of Alzheimer’s disease and related dementias
Amber H. Miller, David E. Marra, Stephen Anton, Demetrius M. Maraganore

Developing and Validating a Computable Phenotype for the Identification of Transgender and Gender Nonconforming Individuals and Subgroups
Yi Guo, Xing He, Tianchen Lyu, Hansi Zhang, Yonghui Wu, Xi Yang, Zhaoyi Chen, Merry Jennifer Markham, François Modave, Mengjun Xie, William Hogan, Christopher A. Harle, Elizabeth A Shenkman, Jiang Bian

Ecologic association between ambient air pollutants and NICU admissions in Florida between 2012 and 2018
K.A. Clarke and E.S. Coker
Environmental Health Perspectives, presented at International Society for Environmental Epidemiology Annual Meeting in August 2020

Characteristics of 24,516 Patients Diagnosed with COVID-19 Illness in a National Clinical Research Network: Results from PCORnet
Jason P. Block, Keith A. Marsolo, Kshema Nagavedu, L. Charles Bailey, Henry Cruz, Christopher B. Forrest, Kevin Haynes, Adrian F. Hernandez, Rainu Kaushal, Abel Kho, Kathleen M. McTigue, Vinit P. Nair, Richard Platt, Jon Puro, Russell L. Rothman, Elizabeth Shenkman, Lemuel Russell Waitman, Mark G. Weiner, Neely Williams, Thomas W. Carton, Network Partners
MedRxiv pre-print, August 4, 2020

Sa1242 Gender Disparities in Upper Endoscopy Among Patients with Gastroesophgeal Reflux Disease (GERD): Findings from a Statewide Clinical Data Research Network
Bashar J. Qumseya, Ramzi Salloum, Dennis Yang, Peter V. Draganov
Gastrointestinal Endoscopy, Poster Abstracts, Volume 91, Issue 6, Supplement AB127, June 1, 2020

242 Low Rates of Endoscopy in Patients with Multiple Risk Factors for Barrestt’s Esophagus: Findinds from a Statewide Research Network
Bashar J. Qumseya, Ramzi Salloum, Dennis Yang, Peter V. Draganov
Gastrointestinal Endoscopy, Oral Abstract, Volume 91, Issue 6, Supplement AB22-AB23, June 1, 2020

163 Endoscopic Full Thickness Resection Compared to Submucosal Tunnel Endoscopic Resection for Treatment of Gastric Gist
Philip Wai Yan W. Chiu, Hon Chi Yip, Shannon M. Chan, Anthony Y. Teoh, Simon K. Wong, Enders K. Ng
Gastrointestinal Endoscopy, Oral Abstracts, Volume 91, Issue 6, Supplement AB22, June 1, 2020

Sa1195 Association between Number of Barrett’s Esophagus (BE) Risk Factors and Disease Prevalence: Statewide Clinical Research Database
Bashar J. Qumseya, Ramzi Salloum, Peter V. Draganov
Gastroenterology, AGA Abstracts, Volume 158, Issue 6, Supplement 1, May 2020, Pages S-307

Su1989 Age-Specific Healthcare Utilization Trends in a Transitional IBD Population
Aniruddh Setya, Isaac Molina, Maher Homsi, Naueen A. Chaudhry, Ziad Suleiman, Wei Xue, Ellen M. Zimmermann
Gastroenterology, AGA Abstracts, Volume 158, Issue 6, Supplement 1, May 2020, Pages S-735

Leverage Real-world Longitudinal Data in Large Clinical Research Networks for Alzheimer’s Disease and Related Dementia (ADRD)
Rui Duan,Zhaoyi Chen, Jiayi Tong, Chongliang Luo, Tianchen Lyu, Cui Tao, Demetrius Maraganore, Jiang Bian, Yong Chen

Identifying Clinical Risk Factors for Opioid Use Disorder using a Distributed Algorithm to Combine Real-World Data from a Large Clinical Data Research Network
Jiayi Tong, Zhaoyi Chen, Rui Duan, Wei-Hsuan Lo-Ciganic, Tianchen Lyu, Cui Tao, Peter A. Merkel, Henry R. Kranzler, Jiang Bian, Yong Chen

An Iterative Process for Identifying Pediatric Patients With Type 1 Diabetes: Retrospective Observational Study
Heather Lynne Morris, William Troy Donahoo, Brittany Bruggeman, Chelsea Zimmerman, Paul Hiers, Victor W Zhong, Desmond Schatz

Optimizing identification of resistant hypertension: Computable phenotype development and validation
Caitrin W. McDonough, Kyle Babcock, Kristen Chucri, Dana C. Crawford, Jiang Bian, François Modave, Rhonda M. Cooper-DeHoff, William R. Hogan

Using Real-World Data to Rationalize Clinical Trials Eligibility Criteria Design: A Case Study of Alzheimer’s Disease Trials
Qian Li, Yi Guo, Zhe He, Hansi Zhang, Thomas J George Jr, Jiang Bian

HCV testing: Order and completion rates among baby boomers obtaining care from seven health systems in Florida, 2015–2017
Susan T. Vadaparampil, Lindsay N. Fuzzell, Julie Rathwell, Richard R. Reich, Elizabeth Shenkman, David R. Nelson, Erin Kobetz, Patricia D. Jones, Richard Roetzheim, Anna R. Giuliano

Use of EHR-Based Pediatric Quality Measures: Views of Health System Leaders and Parents
David M. Hartley, Susannah Jonas, Daniel Grossoehme, Amy Kelly, Cassandra Dodds, Shannon M. Alford, Elizabeth Shenkman, Jeff Simmons, L. Charles Bailey, Hanieh Razzaghi, Levon H. Utidjian, Jennifer McCafferty-Fernandez, F. Sessions Cole, Jordan Smallwood, Lloyd N. Werk, Kathleen E. Walsh

‘How did you get to this number?’ Stakeholder needs for implementing predictive analytics: a pre-implementation qualitative study
Natalie C. Benda, Lala Tanmoy Das, Erika L. Abramson, Katherine Blackburn, Amy Thoman, Rainu Kaushal, Yongkang Zhang, Jessica S. Ancker

The PCORnet Blood Pressure Control Laboratory: A Platform for Surveillance and Efficient Trials
Mark J. Pletcher, Valy Fontil, Thomas Carton, Kathryn M. Shaw, Myra Smith, Sujung Choi, Jonathan Todd, Alanna M. Chamberlain, Emily C. O’Brien, Madelaine Faulkner, Carlos Maeztu, Gregory Wozniak, Michael Rakotz, Christina M. Shay, Rhonda M. Cooper-DeHoff

Comparing the 5-Year Diabetes Outcomes of Sleeve Gastrectomy and Gastric BypassThe National Patient-Centered Clinical Research Network (PCORNet) Bariatric Study
Kathleen M. McTigue, Robert Wellman, Elizabeth Nauman, Jane Anau, R. Yates Coley, Alberto Odor, Julie Tice, Karen J. Coleman, Anita Courcoulas, Roy E. Pardee, Sengwee Toh, Cheri D. Janning, Neely Williams, Andrea Cook, Jessica L. Sturtevant, Casie Horgan, David Arterburn, for the PCORnet Bariatric Study Collaborative

Optimizing Antihypertensive Medication Classification in ElectronicHealth Record-Based Data: Classification System Developmentand Methodological Comparison
Caitrin W McDonough, Steven M Smith, Rhonda M Cooper-DeHoff, William R Hogan

Interventions and Operations 5 Years After Bariatric Surgery in a Cohort From the US National Patient-Centered Clinical Research Network Bariatric Study
Anita Courcoulas, R. Yates Coley, Jeanne M. Clark, Corrigan L. McBride, Elizabeth Cirelli, Kathleen McTigue, David Arterburn, Karen J. Coleman, Robert Wellman, Jane Anau, Sengwee Toh, Cheri D. Janning, Andrea J. Cook, Neely Williams, Jessica L. Sturtevant, Casie Horgan, Ali Tavakkoli, for the PCORnet Bariatric Study Collaborative

“I can be the Judge of What’s Serious”: A Qualitative Pilot Study of Parents’ Responses to Messaging About Side Effects of the HPV Vaccine
Ryan P. Theis, Brittny A. Wells, Stephanie A. S. Staras

2019

Trends in Hydroxyurea Utilization for the Treatment of Sickle Cell Anemia in Florida
Vandy Black, Jasmine A Mack, Jaclyn Hall, Heather Morris, Elizabeth Shenkman, Matthew J Gurka

Mining Twitter to assess the determinants of health behavior toward human papillomavirus vaccination in the United States
Hansi Zhang, Christopher Wheldon, Adam G Dunn, Cui Tao, Jinhai Huo, Rui Zhang, Mattia Prosperi, Yi Guo, Jiang Bian

Drivers of preventable high health care utilization: a qualitative study of patient, physician and health system leader perspectives
Lala Tanmoy Das, Rainu Kaushal, Kelsey Garrison, Vanessa Carrillo, Zachary Grinspan, Ryan Theis, Elizabeth Shenkman, Erika Abramson

What Can We Learn About Drug Safety and Other Effects in the Era of Electronic Health Records and Big Data That We Would Not Be Able to Learn From Classic Epidemiology?
Ali Zarrinpar, Ting-Yuan David Cheng, Zhiguang Huo

Implementing a hash-based privacy-preserving record linkage tool in the OneFlorida clinical research network
Jiang Bian, Alexander Loiacono, Andrei Sura, Tonatiuh Mendoza Viramontes, Gloria Lipori, Yi Guo, Elizabeth Shenkman, William Hogan

The “All of Us” Research Program
The All of Us Research Program Investigators

Advances in the Use of Real- World Evidence for Medical Devices: An Update From the National Evaluation System for Health Technology
Rachael L. Fleurence, Jeffrey Shuren

Assessing the Validity of a a priori Patient-Trial Generalizability Score using Real-world Data from a Large Clinical Data Research Network: A Colorectal Cancer Clinical Trial Case Study
Qian L, Zhe He, Yi Guo, Hansi Zhang, Thomas J George Jr, William Hogan, Neil Charness, Jiang Bian

Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene–drug pairs across ambulatory care settings
Emily J. Cicali, Kristin Wiisanen Weitzel, Amanda R. Elsey, Frank A. Orlando, Michelle Vinson, Scott Mosley, D. Max Smith, Richard Davis, Lori Drum, David Estores, James P. Franciosi, Melanie Gross Hagen, Gabriel J. Jerkins, Elvira S. Mercado, Jaison Nainaparampil, Adaixa Padron, Eric I. Rosenberg, Ashleigh Wright, Siegfried O. Schmidt, Carol A. Mathews, Larisa H. Cavallari, Julie A. Johnson

Shared Care for Adults with Sickle Cell Disease: An Analysis of Care from Eight Health Systems
Arch G. Mainous III, Benjamin Rooks, Rebecca J. Tanner, Peter J. Carek, Vandy Black, Thomas D. Coates

Assessing the Safety of Direct-Acting Antiviral Agents for Hepatitis C
Elizabeth A. McGlynn, John L. Adams, Jason Kramer, Amandeep K. Sahota, Michael J. Silverberg, Elizabeth Shenkman, David R. Nelson

Considerations of Privacy and Confidentiality in Developing a Clinical Support Tool for Adolescent Tobacco Prevention: Qualitative Study
Ryan P. Theis, Ali M. Malik, Lindsay A. Thompson, Elizabeth A. Shenkman, Lori Pbert, Ramzi G. Salloum

Tobacco-Related Counseling and Documentation in Adolescent Primary Care Practice: Challenges and Opportunities
Jennifer H. LeLaurin, Ryan P. Theis, Lindsay A. Thompson, Andy S. L. Tan, Kelly C. Young-Wolff, Lisa Carter-Harris, Elizabeth A. Shenkman, Ramzi G. Salloum

Use of EHR-Based Pediatric Quality Measures: Views of Health System Leaders and Parents
David M. Hartley, Susannah Jonas, Daniel Grossoehme, Amy Kelly, Cassandra Dodds, Shannon M. Alford, Elizabeth Shenkman, Jeff Simmons, L. Charles Bailey, Hanieh Razzaghi, Levon H. Utidjian, Jennifer McCafferty-Fernandez, F. Sessions Cole, Jordan Smallwood, Lloyd N. Werk, Kathleen E. Walsh

PCSK9 Inhibitor Use in the Real World: Data From the National Patient‐Centered Research Network
Alanna M. Chamberlain, Yan Gong, Kathryn McAuliffe Shaw, Jiang Bian, Wen-Liang Song,  MacRae F. Linton, Vivian Fonseca,  Eboni Price-Haywood, Emily Guhl, Jordan B. King, Rashmee U. Shah, Jon Puro, Elizabeth Shenkman, Pamala A. Pawloski, Karen L. Margolis, Adrian F. Hernandez, Rhonda M. Cooper-DeHoff

Hepatitis C virus screening trends: A 2016 update of the National Health Interview Survey
Monica L. Kasting, Anna R. Giuliano, Richard R. Reich, Richard G. Roetzheim, Linh M. Duong, Emmanuel Thomas, David R. Nelson, Elizabeth Shenkman, Susan T. Vadaparampil

Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene–drug pairs across ambulatory care settings
Emily J. Cicali, Kristin Wiisanen Weitzel, Amanda R. Elsey, Frank A. Orlando,  Michelle Vinson, Scott Mosley, D. Max Smith, Richard Davis, Lori Drum, David Estores, James P. Franciosi, Melanie Gross Hagen, Gabriel J. Jerkins, Elvira S. Mercado, Jaison Nainaparampil, Adaixa Padron, Eric I. Rosenberg, Ashleigh Wright, Siegfried O. Schmidt, Carol A. Mathews, Larisa H. Cavallari, Julie A. Johnson

MADEx: A System for Detecting Medications, Adverse Drug Events, and Their Relations from Clinical Notes
Xi Yang, Jiang Bian, Yan Gong, William R. Hogan, Yonghui Wu

Objectively measured pediatric obesity prevalence using the OneFlorida Clinical Research Consortium
Dominick J. Lemas, Michelle I. Cardel, Stephanie L. Filipp, Jaclyn Hall, Rebecca Z. Essner, Steven R. Smith. Joseph Nadglowski, Troy Donahoo, Rhonda M. Cooper-DeHoff, David R.Nelson, William R. Hogan, Elizabeth A. Shenkman, Matthew J. Gurka, David M. Janicke

Performance of a computable phenotype for identification of patients with diabetes within PCORnet: The Patient‐Centered Clinical Research Network
Andrew D. Wiese, Christianne L. Roumie, John B. Buse, Herodes Guzman, Robert Bradford, Emily Zalimeni, Patricia Knoepp, Heather L. Morris, William T. Donahoo, Nada Fanous, Britany F. Epstein, Bonnie L. Katalenich, Sujata G. Ayala, Megan M. Cook, Katherine J. Worley, Katherine N. Bachmann, Carlos G. Grijalva, Russell L. Rothman, Rosette J. Chakkalakal

Assessing the effect of data integration on predictive ability of cancer survival models
Yi Guo, Jiang Bian, Francois Modave, Qian Li, Thomas J George, Mattia Prosperi, Elizabeth Shenkman

Maternal antibiotic use during pregnancy and childhood obesity at age 5 years 
William J. Heerman, Matthew F. Daley, Janne Boone-Heinonen, Sheryl L. Rifas-Shiman, L. Charles Bailey, Christopher B. Forrest, Jessica G. Young, Matthew W. Gillman, Casie E. Horgan, David M. Janicke, Chelsea Jenter, Elyse O. Kharbanda, Doug Lunsford, Mary Jo Messito, Sengwee Toh, Jason P. Block, On behalf of the PCORnet Antibiotics and Childhood Growth Study Group

2018

Comparative Effectiveness and Safety of Bariatric Procedures for Weight Loss-A PCORnet Cohort Study
David Arterburn, Robert Wellman, Ana Emiliano, Steven R. Smith, Andrew O. Odegaard, Sameer Murali, Neely Williams, Karen J. Coleman, Anita Courcoulas, R. Yates Coley, Jane Anau, Roy Pardee, Sengwee Toh, Cheri Janning, Andrea Cook, Jessica Sturtevant, Casie Horgan, Kathleen M. McTigue for the PCORnet Bariatric Study Collaborative
Annals of Internal Medicine, December 4, 2018

2240 High-throughput phenotyping and the increased risk of OSA in Rosacia patients
Peter Elkin, Sarah Mullin, Sanjay Sethi, Shyamashree Sinha, and Animesh Sinha
Cambridge University Press, Journal of Clinical and Translational Science, Volume 1 Supplement S1, 2240 Published online May 10, 2018

2246 Characterization of resistant hypertension in a statewide electronic health record-based database (OneFlorida)
Caitrin W. McDonough, William R. Hogan, Betsy Shenkman, and Rhonda M. Cooper-DeHoff
Cambridge University Press, Journal of Clinical and Translational Science, Volume 1 Supplement S1, 2246 Published online May 10, 2018

Comparative effectiveness of bariatric procedures among adolescents: the PCORnet bariatric study
Thomas H. Inge, R. Yates Coley, Lydia A. Bazzano, Stavra A. Xanthakos, Kathleen McTigue, David Arterburn, Neely Williams, Rob Wellman, Karen J. Coleman, Anita Courcoulas, Nirav K. Desai, Jane Anau, Roy Pardee, Sengwee Toh, Cheri Janning, Andrea Cook, Jessica Sturtevant, Casie Horgan, Ava J. Zebrick, Marc Michalsky
Science Direct Online, Received 8 January 2018, Revised 28 March 2018, Accepted 5 April 2018, Available online 17 April 2018

An ontology-guided semantic data integration framework to support integrative data analysis of cancer survival
Hansi Zhang, Yi Guo, Qian Li, Thomas J. George, Elizabeth Shenkman, François Modave, Jiang Bian

OC-2-KB: integrating crowdsourcing into an obesity and cancer knowledge base curation system
Juan Antonio Lossio-Ventura, William Hogan, François Modave, Yi Guo, Zhe He, Xi Yang, Hansi Zhang, Jiang Bian

Hepatitis C Virus Screening Trends: Serial Cross-Sectional Analysis of the National Health Interview Survey Population, 2013–2015
Monica L. Kasting, Anna R. Giuliano, Richard R. Reich, Richard G. Roetzheim, David R. Nelson, Elizabeth Shenkman, Susan T. Vadaparampil

Computable Eligibility Criteria through Ontology-driven Data Access: A Case Study of Hepatitis C Virus Trials
Hansi Zhang, Zhe He, Xing He, Yi Guo, David R. Nelson, François Modave, Yonghui Wu, William Hogan, Mattia Prosperi, Jiang Bian

PCORnet’s Collaborative Research Groups
Mark J. Pletcher, Christopher B. Forrest, Thomas W. Carton

Rural-urban and racial-ethnic differences in awareness of direct-to-consumer genetic testing
Ramzi G. Salloum, Thomas J. George, Natalie Silver, Merry-Jennifer Markham, Jaclyn M. Hall, Yi Guo, Jiang Bian, Elizabeth A. Shenkman

Participatory implementation science to increase the impact of evidence-based cancer prevention and control
Shoba Ramanadhan, Melinda M. Davis, Rebecca Armstrong, Barbara Baquero, Linda K. Ko, Jennifer C. Leng, Ramzi G. Salloum, Nicole A. Vaughn, Ross C. Brownson

Big Data Hurdles in Precision Medicine and Precision Public Health
Mattia Prosperi, Jae S. Min, Jiang Bian, François Modave

Stakeholder Engagement in Developing an Electronic Clinical Support Tool for Tobacco Prevention in Adolescent Primary
Ramzi G. Salloum, Ryan P. Theis, Lori Pbert, Matthew J. Gurka, Maribeth Porter, Diana Lee, Elizabeth A. Shenkman, Lindsay A. Thompson

Early Antibiotic Exposure and Weight Outcomes in Young Children
Jason P. Block, L. Charles Bailey, Matthew W. Gillman, Doug Lunsford, Matthew F. Daley, Ihuoma Eneli, Jonathan Finkelstein, William Heerman, Casie E. Horgan, Daniel S. Hsia, Melanie Jay, Goutham Rao, Juliane S. Reynolds, Sheryl L. Rifas-Shiman, Jessica L. Sturtevant, Sengwee Toh, Leonardo Trasande, Jessica Young, Christopher B. Forrest, on behalf of the PCORnet Antibiotics and Childhood Growth Study Group

OC-2-KB: integrating crowdsourcing into an obesity and cancer knowledge base curation system
Juan Antonio Lossio-Ventura, William Hogan, François Modave, Yi Guo, Zhe He, Xi Yang, Hansi Zhang, Jiang Bian

Characterization of Adult Obesity in Florida Using the OneFlorida Clinical Research Consortium
S. L. Filipp, M. Cardel, J. Hall, R. Z. Essner, D. J. Lemas, D. M. Janicke, S. R. Smith, J. Nadglowski, W. Troy Donahoo, R. M. Cooper‐DeHoff, D. R. Nelson, W. R. Hogan, E. A. Shenkman, M. J. Gurka

Hypertension in Florida: Data From the OneFlorida Clinical Data Research Network
Steven M. Smith, Kathryn McAuliffe, Jaclyn M. Hall, Caitrin W. McDonough, Matthew J. Gurka, Temple O. Robinson, Ralph L. Sacco, Carl Pepine, Elizabeth Shenkman, Rhonda M. Cooper-DeHoff

Prevalence of Multiple Chronic Conditions Among Older Adults in Florida and the United States: Comparative Analysis of the OneFlorida Data Trust and National Inpatient Sample
Zhe He, Jiang Bian, Henry J Carretta, Jiwon Lee, William R Hogan, Elizabeth Shenkman, Neil Charness

The PCORnet Antibiotics and Childhood Growth Study: Process for Cohort Creation and Cohort Description
Jason P. Block, L. Charles Bailey, Matthew W. Gillman, Douglas Lunsford, Janne Boone-Heinonen, Lauren P. Cleveland, Jonathan Finkelstein, Casie Horgan, Melanie Jay, Juliane S. Reynolds, Jessica Sturtevant, Christopher B. Forrest, On behalf of the PCORnet Antibiotics and Childhood Growth Study Group

Introducing Hypertension FACTS: Vital Sign Ontology Annotations in the Florida Annotated Corpus for Translational Science
Amanda Hicks, William Hogan, Carl Pepine, Nathan Boire, Chloe Herring, Selja Seppälä2

Using Instructional Design to Support Community Engagement in Clinical and Translational Research: a Design and Development Case
Natercia Valle, Janet Brishke, Albert D. Ritzhaupt, Christy Evans, David R. Nelson, Elizabeth Shenkman

2017

Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus
Zhe He, Arturo Gonzalez-Izquierdo, Spiros Denaxas, Andrei Sura, Yi Guo, William R. Hogan, Elizabeth Shenkman, Jiang Bian

Data Integration through Ontology-Based Data Access to Support Integrative Data Analysis: A Case Study of Cancer Survival
Hansi Zhang, Yi Guo, Qian Li, Thomas J. George, Elizabeth A. Shenkman, Jiang Bian

Identifying High Health Care Utilizers Using Post-Regression Residual Analysis of Health Expenditures from a State Medicaid Program
Chengliang Yang, Chris Delcher, Elizabeth Shenkman, Sanjay Ranka

Implementing a Hash-based Privacy-Preserving Entity Resolution Tool in the OneFlorida Clinical Data Research Network
Jiang Bian

Machine Learning Approaches for Predicting High Utilizers in Health Care
Chengliang Yang, Chris Delcher, Elizabeth Shenkman, Sanjay Ranka

OneFlorida Clinical Research Consortium: Linking a Clinical and Translational Science Institute With a Community-Based Distributive Medical Education Model
Elizabeth Shenkman, Myra Hurt, William Hogan, Olveen Carrasquillo, Steven Smith, Andrew Brickman, David Nelson

The Building Blocks of Inter-operability: A Multisite Analysis of Patient Demographic Attributes Available for Matching
Adam Culbertson, Satyender Goel, Margaret B. Madden, Niloufar Safaeinili, Kathryn L. Jackson, Thomas Carton, Russ Waitman, Mei Liu, Ashok Krishnamurthy, Lauren Hall, Nickie Cappella, Shyam Visweswaran, Michael J. Becich, Reuben Applegate, Elmer Bernstam, Russell Rothman, Michael Matheny, Gloria Lipori, Jiang Bian, William Hogan, Douglas Bell, Andrew Martin, Shaun Grannis, Jeff Klann, Rebecca Sutphen, Amy B. O’Hara, Abel Kho

The National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study Cohort: Rationale, Methods, and Baseline Characteristics
Sengwee Toh, Laura J. Rasmussen-Torvik, Emily E. Harmata, Roy Pardee, Rosalinde Saizan, Elisha Malanga, Jessica L. Sturtevant, Casie Horgan, Jane Anau, Cheri D. Janning, Robert D. Wellman, Yates Colley, Andrea J. Cook, Anita P. Courcoulas, Karen J. Coleman, Neely A. Williams, Kathleen M. McTigue, David Arterburn, James McClay, PCORnet Bariatric Surgery Collaboraitve

Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request
William R. Hogan, Josh Hanna, Amanda Hicks, Samira Amirova, Baxter Bramblett, Matthew Diller, Rodel Enderez, Timothy Modzelewski, Mirela Vasconcelos and Chris Delcher

Towards a privacy preserving cohort discovery framework for clinical research networks
Jiawei Yuan, Bradley Malin, François Modave, Yi Guo, William R. Hogan, Elizabeth Shenkman and Jiang Bian

Using Social Media Data to Understand the Impact of Promotional Information on Laypeople’s Discussions: A Case Study of Lynch Syndrome
Jiang Bian, Yunpeng Zhao, Ramzi G Salloum, Yi Guo, Mo Wang, Mattia Prosperi, Hansi Zhang, Xinsong Du, Laura J Ramirez-Diaz, Zhe He, Yuan Sun

2016

Patterns of Waterpipe Tobacco Smoking Among U.S. Young Adults, 2013−2014
Ramzi G. Salloum, James F. Thrasher, Kayla R. Getz, Tracey E. Barnett, Taghrid Asfar and Wasim Maziak

Predicting 30-Day All-Cause Readmissions from Hospital Inpatient Discharge Data
Chengliang Yang, Chris Delcher, Elizabeth Shenkman, and Sanjay Ranka

The ontology of medically related social entities: recent developments
Amanda Hicks, Josh Hanna, Daniel Welch, Mathias Brochhausen and William R. Hogan

Toward a Regulatory Framework for the Waterpipe
Ramzi G. Salloum, Taghrid Asfar, and Wasim Maziak

Use of Electronic Cigarettes Among Cancer Survivors in the U.S.
Ramzi G. Salloum, Kayla R. Getz, Andy S.L. Tan, Lisa Carter-Harris, Kelly C. Young-Wolff, Thomas J. George Jr. and Elizabeth A. Shenkman

Waterpipe Tobacco Smoking and Susceptibility to Cigarette Smoking Among Young Adults in the United States, 2012–2013
Ramzi G. Salloum, M. Rifat Haider, Tracey E. Barnett, Yi Guo, Kayla R. Getz, James F. Thrasher and Wasim Maziak

2015

The OneFlorida Data Trust: Achieving Health Equity through Research & Training Capacity Building
Proceedings of the 8th Annual Conference on the Science of Dissemination and Implementation: Washington, DC, USA. 14-15 December 2015.

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